DBCO-PEG-NHS Ester

DBCO-PEG-NHS Ester is a heterobifunctional PEG reagent, also known as Cyclooctyne-PEG-NHS ester, combining a DBCO group for copper-free click chemistry with azides and an NHS ester for efficient amine coupling. The NHS ester reacts immediately with primary amines under mild conditions, while the DBCO enables rapid, bioorthogonal cycloaddition without copper catalysts. DBCO-PEG-NHS Ester reagents are ideal for sensitive applications like live-cell labeling, protein conjugation, and in vivo bioconjugation.