Thiol-PEG-t-Butyl ester

Thiol-PEG-t-Butyl Ester is a heterobifunctional PEG reagent featuring a thiol group for conjugation with maleimides or gold surfaces and a tert-butyl-protected carboxylic acid that can be deprotected under acidic conditions. The tert-butyl ester group provides stability during synthesis and storage, while the thiol enables site-specific bioconjugation. These reagents are ideal for sequential conjugation strategies in peptide synthesis and nanomaterial functionalization.