CBZ-PEG-Propionic acid

CBZ-PEG-Propionic acid is a heterobifunctional reagent designed for temporary amine protection and extended spacer-assisted carboxyl conjugation in peptide synthesis and bioconjugation. Its key advantages include hydrogenolysis-labile Cbz deprotection under mild conditions, reduced steric hindrance due to the elongated chain, and tunable PEG length (n) for optimized solubility, though the carboxyl group requires activation for amidation and the Cbz group is sensitive to reducing agents.