Biotin-PEG-Amine

The Biotin-PEGn-Amine series, exemplified by Biotin-PEG4-Amine, is a versatile bioconjugation reagent designed for labeling and purification applications. This heterobifunctional molecule features a terminal amine group for covalent coupling to carboxyl groups or other reactive sites on target molecules (such as proteins, antibodies, and nanoparticles), along with a biotin moiety for high-affinity streptavidin binding. Its key benefits include enhanced water solubility, minimized steric interference afforded by the tunable PEG spacer (n), and highly specific detection or capture through the robust streptavidin-biotin interaction, making it ideal for immunoassays, biosensing, and affinity purification.