Biotin-PEG-Acid

The Biotin-PEGn-Acid series, exemplified by Biotin-PEG4-Acid, is a versatile bioconjugation reagent designed for labeling and purification applications. This heterobifunctional molecule features a terminal carboxylic acid group for covalent attachment to amines and a biotin moiety for high-affinity streptavidin/avidin binding. Its key benefits include enhanced water solubility, minimized steric hindrance, and improved biocompatibility conferred by the tunable PEG spacer (n). These properties enable efficient target capture and detection in various assay systems, including ELISA, pull-down assays, and biosensing platforms.