Fmoc-PEG-NHS ester
The Fmoc-PEG-NHS ester series, exemplified by N-Fmoc-PEG8-CH₂CH₂COONHS Ester, is a heterobifunctional reagent engineered for solid-phase peptide synthesis (SPPS) and conjugate preparation. This integrated molecule combines an Fmoc-protected amine for controlled peptide elongation with a pre-activated NHS ester for efficient amine-reactive conjugation, connected by a tunable PEG spacer. Its key advantages include rapid coupling under physiological conditions, customizable spacer length (n), and dual functionality for protection and conjugation in a single construct.
