Boc-PEG-Bromide

Boc-PEG-Bromide is a heterobifunctional reagent designed for temporary amine protection and nucleophilic substitution (e.g., with thiols or amines) via the bromide terminal group in organic synthesis and bioconjugation. Its key advantages include orthogonal reactivity for sequential modifications, tunable spacer length (n), and cost-effective synthesis, though the bromide group is highly moisture-sensitive and requires anhydrous handling to prevent hydrolysis.