Propargyl-PEG-Thiol

Propargyl-PEG-Thiol is a heterobifunctional PEG reagent, also known as Alkyne-terminated PEG-thiol, combining a terminal alkyne for copper-catalyzed click chemistry and a thiol for site-specific conjugation with maleimides or gold surfaces. The thiol enables stable thioether bond formation, while the alkyne allows efficient cycloaddition with azides. Propargyl-PEG-Thiol reagents are ideal for constructing biomolecular assemblies, functionalized nanoparticles, and biosensing platforms via orthogonal conjugation strategies.