Bis-hydrazide PEG

Hydrazide-PEGn-Hydrazide is a homobifunctional crosslinker designed for conjugating carbonyl groups (e.g., in glycoproteins or oxidized antibodies) via dual hydrazone bond formation. Its key advantages include high selectivity for carbonyl-based ligation, tunable spacer length (n), and enhanced stability under physiological conditions, though the hydrazone linkage may exhibit limited stability in highly acidic or alkaline environments.