Boc-NH-PEG16-CH2CH2COOH

PurePEG High purity Boc-NH-PEG16-CH2CH2COOH is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine. PurePEG’s High Purity Boc-NH-PEG16-CH2CH2COOH has an exact number of PEG units, with a specific chemical structure and precise molecular weight.