Cleavable Linkers

A class of bioconjugation linkers—including Cleavable Linkers and Cleavable Spacers—designed to be specifically cleaved by endogenous enzymes such as proteases and esterases. They enable controlled release of active payloads in target tissues or cellular compartments and are widely used in prodrug design, antibody-drug conjugates (ADCs), and targeted drug delivery systems for precise therapeutic activation.

Similar Products: Disulfide Linkers.

Showing 1–12 of 199 resultsSorted by latest

  Item # CAS # M.F M.W
2-(pyridin-2-yldisulfanyl)ethanol Ethanol 1113 111625-28-2 C7H9NOS2 187.3
  Item # CAS # M.F M.W
Alloc-Val-Ala-OH 51019 330970-70-2 C12H20N2O5 272.13
  Item # CAS # M.F M.W
Alloc-Val-Ala-PAB-PNP 51020 1884578-27-1 C26H30N4O9 542.54
  Item # CAS # M.F M.W
Alloc-Val-Ala-PAB 51051 1343407-91-9 C19H27N3O5 377.4
  Item # CAS # M.F M.W
Z-Val-Cit-OH 51032 159858-06-7 C19H28N4O6 408.45
  Item # CAS # M.F M.W
Alkyne-Val-Cit-PAB-OH 51041 2748039-76-9 C24H35N5O5 473.6
  Item # CAS # M.F M.W
Alkyne-Val-Cit-PAB-PNP 51042 2748039-77-0 C31H38N6O9 638.75
  Item # CAS # M.F M.W
6-Azidohexanoyl-Val-Cit-PAB 51047 1613321-01-9 C24H38N8O5 518.61
  Item # CAS # M.F M.W
SPDP-Val-Cit-PAB-OH 51053 N/A C26H36N6O5S2 576.7
  Item # CAS # M.F M.W
SPDP-Val-Cit-PAB-PNP 51054 N/A C33H39N7O9S2 741.8
  Item # CAS # M.F M.W
MC (C5)-Val-Cit 51055 2504147-59-3 C20H31N5O7 453.5
  Item # CAS # M.F M.W
MC-Val-Cit-PAB-PNP 51057 159857-81-5 C35H43N7O11 737.8