Fmoc-NH-PEG3-CH2COOH

PurePEG High Purity Fmoc-NH-PEG3-CH2COOH is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. PurePEG’s High Purity Fmoc-NH-PEG3-CH2COOH has an exact number of PEG units, with a specific chemical structure and precise molecular weight.