mPEG-Mal

mPEGn-NH-Mal is specifically designed for thiol-reactive conjugation via maleimide chemistry, enabling stable PEGylation of cysteine-containing proteins, peptides, and thiol-functionalized nanoparticles. Its key advantages include high selectivity under physiological pH, rapid reaction kinetics, and tunable PEG length (n) to optimize stability and solubility, though maleimide hydrolysis and retro-Michael reactions may occur in certain conditions.