Boc-PEG-OH

Boc-PEG-OH is a heterobifunctional PEG derivative designed for temporary amine protection in organic synthesis and peptide chemistry, allowing orthogonal deprotection under mild acidic conditions while enabling hydroxyl-terminal modifications. Its key advantages include excellent Boc-group stability under basic conditions, tunable spacer length (n), and enhanced solubility for synthetic intermediates, though the Boc group requires acidolysis for removal and may exhibit limited stability in strong nucleophilic environments.