Biotin-PEG-Azide
The Biotin-PEGn-CH₂CH₂N₃ series, exemplified by Biotin-PEG4-CH₂CH₂N₃, is a heterobifunctional reagent designed for bioorthogonal click chemistry applications. It enables efficient labeling and conjugation of biomolecules through copper-catalyzed (CuAAC) or strain-promoted (SPAAC) azide-alkyne cycloaddition with alkyne-modified targets. The extended PEG spacer significantly reduces steric hindrance and enhances aqueous solubility, while the terminal biotin moiety facilitates robust capture or detection via high-affinity streptavidin-biotin interaction. This combination makes the series particularly valuable for diverse applications including biomolecular imaging, affinity purification, and diagnostic assay development.
| Item # | CAS # | M.F | M.W | ||
|---|---|---|---|---|---|
| 245602 | 1910803-72-3, 945633-30-7 | C16H28N6SO4 | 400.5 | |
| Item # | CAS # | M.F | M.W | ||
| 245603 | 875770-34-6 | C18H32N6SO5 | 444.55 | |
| Item # | CAS # | M.F | M.W | ||
| 245604 | 1309649-57-7 | C20H36N6SO6 | 488.6 | |
| Item # | CAS # | M.F | M.W | ||
| 245605 | 1163732-89-5 | C22H40N6SO7 | 532.65 | |
| Item # | CAS # | M.F | M.W | ||
| 245611 | 956494-20-5 | C34H64N6O13S | 796.97 | |
| Item # | CAS # | M.F | M.W | ||
| 245623 | 956494-20-5 | C58H112N6SO25 | 1325.62 | |