mPEG-Amide-SPDP (cleavable)

mPEG-Amide-SPDP conjugates a monomethoxy polyethylene glycol chain to an SPDP (N‑succinimidyl 3‑(2‑pyridyldithio)propionate) moiety through a stable amide linkage. The SPDP group in mPEG-Amide-SPDP provides an amine‑reactive NHS ester and a pyridyl disulfide for thiol conjugation and reversible disulfide exchange. mPEG-Amide-SPDP is particularly suitable for constructing controlled bioconjugates, reversible protein‑PEGylation, and stimuli‑responsive drug delivery systems.