Propargyl-PEG-NHS Ester

Propargyl-PEG-NHS Ester is a heterobifunctional PEG reagent, also known as Propargyl-functional PEG-NHS, combining a terminal alkyne for copper-catalyzed azide-alkyne cycloaddition (CuAAC) and an NHS ester for efficient amine coupling. The NHS ester enables rapid conjugation with primary amines under mild conditions, while the alkyne allows subsequent bioorthogonal click chemistry with azides. Propargyl-PEG-NHS Ester reagents are ideal for sequential bioconjugation in protein labeling, biomaterial modification, and diagnostic probe construction.