Boc-PEG-Propionic acid

Boc-PEG-Propionic acid is a heterobifunctional reagent designed for temporary amine protection and extended spacer-assisted carboxyl conjugation in peptide synthesis and bioconjugation. Its key advantages include mild acid-labile Boc deprotection, reduced steric hindrance due to the elongated chain, and tunable PEG length (n) for optimized solubility, though the carboxyl group requires activation for amidation and the Boc group may be incompatible with strong electrophiles.