mPEG-Propargyl

mPEGn-Propargyl is widely utilized in copper-free click chemistry (e.g., SPAAC) for conjugating with azide-functionalized biomolecules, enabling efficient PEGylation of antibodies, proteins, and nanoparticles under physiological conditions. Its key advantages include rapid reaction kinetics, excellent bioorthogonality, and tunable PEG length (n) to optimize solubility and stability, though terminal alkyne oxidation may require inert handling conditions.