Bis-Propargyl PEG

Bis-Propargyl PEGn is a homobifunctional alkyne-PEG derivative designed for dual copper-catalyzed azide-alkyne cycloaddition (CuAAC), enabling symmetric crosslinking of azide-functionalized molecules (e.g., proteins, peptides, or nanoparticles). Its key advantages include high click chemistry efficiency, tunable spacer length (n) for optimized distance control, and stable triazole linkage formation, though copper catalysts may introduce cytotoxicity and require removal for biological applications.