Maleimide-PEG-Amine

Maleimide-PEG-Amine combines a maleimide group for thiol-specific conjugation with a primary amine for covalent attachment to carboxyl groups or other reactive sites. The PEG spacer in Maleimide-PEG-Amine provides enhanced hydrophilicity and reduces steric hindrance. Maleimide-PEG-Amine is widely used for constructing antibody-drug conjugates, protein-protein crosslinks, and functionalized biomaterials requiring orthogonal amine and thiol reactivity.