Bromo-PEG-Acid

Br-PEGn-CH₂COOH is a heterobifunctional PEG derivative designed for dual conjugation strategies, enabling sequential nucleophilic substitution (e.g., with thiols or amines) via the bromide group followed by carboxyl-mediated amide bond formation. Its key advantages include orthogonal reactivity for flexible biomolecular assembly, tunable spacer length (n), and cost-effective synthesis, though the bromide group is moisture-sensitive and may require anhydrous handling to prevent hydrolysis.