Biotin-LC-hydrazide

Biotin-LC-hydrazide is specifically designed for conjugation with carbonyl groups (e.g., aldehydes in glycoproteins or oxidized sugars), combining the accessibility of a long-chain (LC) biotin spacer with hydrazone linkage specificity. Its key advantages include selective labeling of glycans and oxidized biomolecules, reduced steric hindrance for improved streptavidin binding, and compatibility with carbohydrate-specific detection workflows, though the hydrazone bond may exhibit limited stability under highly acidic conditions.