mPEG-SMG

mPEGn-SMG (succinimidyl methyl glycolate) is specifically designed for hydrolyzable PEGylation, enabling controlled release of conjugated drugs or biomolecules through ester bond cleavage under physiological conditions. It is particularly valuable for prodrug development and transient modification of therapeutics, though its hydrolysis rate depends on pH and enzymatic activity, requiring careful optimization for specific applications.

  Item # CAS # M.F M.W
mPEG24-SMG 367524 N/A C66H132O28 1373.74
  Item # CAS # M.F M.W
mPEG45-SMG 367545 N/A C108H216O49 2298.84