Biotin-SLC-NHS ester

Biotin-SLC-NHS Ester is designed for efficient bioconjugation with amine groups in sterically constrained environments, such as small molecule modifications or dense protein surfaces, leveraging its short chain (SLC) to minimize distance-related binding issues. Its key advantages include high reactivity under mild conditions, reduced hydrophobic impact compared to longer chains, and optimal performance in applications requiring close proximity labeling, though the NHS ester group requires careful anhydrous handling to prevent hydrolysis.