BET Bromodomain Inhibitors

A group of epigenetic modulators that selectively bind to bromodomain and extra-terminal (BET) family proteins (BRD2, BRD3, BRD4, BRDT), thereby disrupting their interaction with acetylated histones and transcription factors. This inhibition leads to downregulation of oncogenic and inflammatory gene expression, offering therapeutic potential in oncology, inflammatory diseases, and cardiovascular disorders through precise transcriptional regulation.

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